A broadly applicable [18F]trifluoromethylation of aryl and heteroaryl iodides for PET imaging.

Abstract

Molecules labelled with the unnatural isotope fluorine-18 are used for positron emission tomography. Currently, this molecular imaging technology is not exploited at its full potential because many (18)F-labelled probes are inaccessible or notoriously difficult to produce. Typical challenges associated with (18)F radiochemistry are the short half-life of… (More)
DOI: 10.1038/nchem.1756

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