A broad-spectrum organophosphate pesticide O,O-dimethyl O-4-nitrophenyl phosphorothioate (methyl parathion) adversely affects the structure and function of male accessory reproductive organs in the rat.

@article{Narayana2006ABO,
  title={A broad-spectrum organophosphate pesticide O,O-dimethyl O-4-nitrophenyl phosphorothioate (methyl parathion) adversely affects the structure and function of male accessory reproductive organs in the rat.},
  author={Kilarkaje Narayana and Narayan Prashanthi and Arunkumar Nayanatara and S Ganesh Kumar and H Harish Chandra Kumar and K. Laxminarayana Bairy and Urban J A D'Souza},
  journal={Environmental toxicology and pharmacology},
  year={2006},
  volume={22 3},
  pages={315-24}
}
Methyl parathion (MP) is an organophosphate pesticide used in agriculture, but also illegally used to spray homes and businesses to control insects. The present study was designed to investigate adverse effects of MP on accessory reproductive organs. Male Wistar rats aged 13-14 weeks were treated and sacrificed as follows. Experiment 1: 0.0 (water vehicle), 1.75, 3.5 or 7mg/kg (i.p.) for 5 days and sacrificed on day 14; experiment 2: 0.0, 0.5 or 1mg/kg (i.p.) for 12 days and sacrificed on day… CONTINUE READING