A brain-specific cytochrome P450 responsible for the majority of deltamethrin resistance in the QTC279 strain of Tribolium castaneum.

@article{Zhu2010ABC,
  title={A brain-specific cytochrome P450 responsible for the majority of deltamethrin resistance in the QTC279 strain of Tribolium castaneum.},
  author={Fang Zhu and Raghuveer Parthasarathy and Hua Bai and Katharina Woithe and Martin Kaussmann and Ralf Nauen and Douglas A. Harrison and Subba Reddy Palli},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2010},
  volume={107 19},
  pages={8557-62}
}
Cytochrome P450-mediated detoxification is one of the most important mechanisms involved in insecticide resistance. However, the molecular basis of this mechanism and the physiological functions of P450s associated with insecticide resistance remain largely unknown. Here, we exploited the functional genomics and reverse genetic approaches to identify and… CONTINUE READING