A biphasic tumor of the mediastinum with features of synovial sarcoma. A report of four cases.

@article{Witkin1989ABT,
  title={A biphasic tumor of the mediastinum with features of synovial sarcoma. A report of four cases.},
  author={Georgia Witkin and Markku Miettinen and Juan Rosai},
  journal={The American journal of surgical pathology},
  year={1989},
  volume={13 6},
  pages={
          490-9
        }
}
Four cases of a biphasic mediastinal tumor histologically identical to synovial sarcoma of soft tissue were observed. The tumors presented as solitary mediastinal masses. Although the tumors were frequently adherent to adjacent pleura or pericardium, none appeared to be arising from a mesothelial surface. All cases were composed of an intimate admixture of keratin-positive epithelial cells and vimentin-positive spindle cells with areas of transition, hyalinization, and calcification. Follow-up… CONTINUE READING
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