A biosynthetic regulated secretory pathway in constitutive secretory cells

@article{Chavez1996ABR,
  title={A biosynthetic regulated secretory pathway in constitutive secretory cells},
  author={Raymond A. Chavez and Stephen G. Miller and Harvey A. Moore},
  journal={The Journal of Cell Biology},
  year={1996},
  volume={133},
  pages={1177 - 1191}
}
It has frequently been proposed that while the constitutive secretory pathway is present in all cells, the regulated secretory pathway is found only in specialized cells such as neuronal, endocrine, or exocrine types. In this study we provide evidence that suggests that this distinction is not as restrictive as proposed. We have identified a population of post-Golgi storage vesicles in several constitutive secretory cells using [35S]SO4-labeled glycosaminoglycan (GAG) chains as a marker. A… CONTINUE READING

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