A bioorganometallic approach for the electrochemical detection of proteins: a study on the interaction of ferrocene-peptide conjugates with papain in solution and on Au surfaces.

Abstract

In this paper, a new bioorganometallic approach for the detection of proteins using surface-bound ferrocene-peptide conjugates is presented. Specifically, a series of peptide conjugates of 1'-aminoferrocene-1-carboxylic acid (ferrocene amino acid, Fca) is synthesized: Boc-Fca-Gly-Gly-Tyr(Bzl)-Arg(NO2)-OMe (2), Thc-Fca-Gly-Gly-Tyr(Bzl)-Arg(NO2)-OMe (3), Thc… (More)

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@article{Mahmoud2007ABA, title={A bioorganometallic approach for the electrochemical detection of proteins: a study on the interaction of ferrocene-peptide conjugates with papain in solution and on Au surfaces.}, author={Khaled A Mahmoud and Heinz-Bernhard Kraatz}, journal={Chemistry}, year={2007}, volume={13 20}, pages={5885-95} }