A biomimetic porous hydrogel of gelatin and glycosaminoglycans cross-linked with transglutaminase and its application in the culture of hepatocytes.

@article{Colli2012ABP,
  title={A biomimetic porous hydrogel of gelatin and glycosaminoglycans cross-linked with transglutaminase and its application in the culture of hepatocytes.},
  author={Marianna De Colli and Mara Massimi and Andrea Barbetta and Biancalucia Di Rosario and Stefania Nardecchia and Laura Conti Devirgiliis and Mariella Dentini},
  journal={Biomedical materials},
  year={2012},
  volume={7 5},
  pages={055005}
}
The development of blended gelatin and glycosaminoglycan (GAG) scaffolds can potentially be used in many soft tissue engineering applications since these scaffolds mimic the structure and biological function of native extracellular matrix (ECM). In this study, we were able to obtain a gelatin-GAG scaffold by using a concentrated emulsion templating technique known as high internal phase emulsion (HIPE), in which a prevailing in volume organic phase is dispersed in the form of discrete droplets… CONTINUE READING
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