A bioluminescent microbial biosensor for in vitro pretreatment assessment of cytarabine efficacy in leukemia.

Abstract

BACKGROUND The nucleoside analog cytarabine (Ara-C [cytosine arabinoside]) is the key agent for treating acute myeloid leukemia (AML); however, up to 30% of patients fail to respond to treatment. Screening of patient blood samples to determine drug response before commencement of treatment is needed. This project aimed to construct and evaluate a self… (More)
DOI: 10.1373/clinchem.2010.145581

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Cite this paper

@article{Alloush2010ABM, title={A bioluminescent microbial biosensor for in vitro pretreatment assessment of cytarabine efficacy in leukemia.}, author={Habib M. Alloush and Elizabeth Anderson and Ashley D Martin and Mark W. Ruddock and Johanna E Angell and Phil J Hill and Priyanka Mehta and M Ann Smith and John Graham Smith and Vyv C Salisbury}, journal={Clinical chemistry}, year={2010}, volume={56 12}, pages={1862-70} }