A biologybased biologybased biologybased dynamic approach for the modelling of toxicity in cell-based assays . Part I : Fate modelling

@inproceedings{Zaldvar2010ABB,
  title={A biologybased biologybased biologybased dynamic approach for the modelling of toxicity in cell-based assays . Part I : Fate modelling},
  author={J. M. Zald{\'i}var and Milena Mennecozzi and Rance Rodrigues and Mounir Bouhifd},
  year={2010}
}
There is a need to integrate existing in vitro dose-response data in a coherent framework for extending their domain of applicability as well as their extrapolation potential. This integration would contribute towards the reduction of animal use in toxicology by using in vitro data for quantitative risk assessment; moreover it would reduce costs and time especially when such approaches would be used for dealing with complex human health and ecotoxicological endpoints. In this work, based on HTS… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 34 references

Measuring, modelling and increasing the free concentration of test chemicals

  • N. I. Kramer
  • 2010
Highly Influential
8 Excerpts

A simple microplate algal assay technique for aquatic toxicity assessment

  • C. Blaise, R. Legault, N. Bermingham, R. Van Coillie, P. Vasseur
  • Toxic. Assess. 1, 261-281.
  • 1986
Highly Influential
6 Excerpts

A new method for prediction of binary gas phase

  • E. N. Fuller, P. D. Schettler, J. C. Giddings
  • diffusion coefficients. Ind. Eng. Chem. 58, 18-27…
  • 1966
Highly Influential
2 Excerpts

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