A biological clock in Drosophila.

  title={A biological clock in Drosophila.},
  author={Michael W. Young and Fannie R. Jackson and Hyung Sik Shin and Thaddeus A. Bargiello},
  journal={Cold Spring Harbor symposia on quantitative biology},
The per locus plays a central role in the organization and function of the Drosophila biological clock. The gene has been mapped to a 7-kb DNA segment by physically locating the breakpoints of several chromosomal rearrangements that disrupt per function. This DNA contains a single transcription unit which produces a 4.5-kb poly(A)+ RNA. No oscillation in the synthesis of this transcript is detected when per expression is followed over a 24-hour cycle of light and dark. When wild-type DNA… CONTINUE READING


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