A biolayer interferometry-based assay for rapid and highly sensitive detection of biowarfare agents.

@article{Mechaly2016ABI,
  title={A biolayer interferometry-based assay for rapid and highly sensitive detection of biowarfare agents.},
  author={Adva Mechaly and Hila Cohen and Ofer Cohen and Ohad Mazor},
  journal={Analytical biochemistry},
  year={2016},
  volume={506},
  pages={
          22-7
        }
}
Biolayer interferometry (BLI) is an optical technique that uses fiber-optic biosensors for label-free real-time monitoring of protein-protein interactions. In this study, we coupled the advantages of the Octet Red BLI system (automation, fluidics-free, and on-line monitoring) with a signal enhancement step and developed a rapid and sensitive immunological-based method for detection of biowarfare agents. As a proof of concept, we chose to demonstrate the efficacy of this novel assay for the… CONTINUE READING
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