A bioinformatic approach to understanding antibiotic resistance in intracellular bacteria through whole genome analysis.

@article{Biswas2008ABA,
  title={A bioinformatic approach to understanding antibiotic resistance in intracellular bacteria through whole genome analysis.},
  author={Silpak Biswas and Didier Raoult and Jean Marc Rolain},
  journal={International journal of antimicrobial agents},
  year={2008},
  volume={32 3},
  pages={207-20}
}
Intracellular bacteria survive within eukaryotic host cells and are difficult to kill with certain antibiotics. As a result, antibiotic resistance in intracellular bacteria is becoming commonplace in healthcare institutions. Owing to the lack of methods available for transforming these bacteria, we evaluated the mechanisms of resistance using molecular methods and in silico genome analysis. The objective of this review was to understand the molecular mechanisms of antibiotic resistance through… CONTINUE READING
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