A bioenergetic mechanism for amoeboid-like cell motility profiles tested in a microfluidic electrotaxis assay.

Abstract

The amoeboid-like cell motility is known to be driven by the acidic enzymatic hydrolysis of ATP in the actin-myosin system. However, the electro-mechano-chemical coupling, whereby the free energy of ATP hydrolysis is transformed into the power of electrically polarized cell movement, is poorly understood. Previous experimental studies showed that actin… (More)
DOI: 10.1039/c7ib00086c

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