A bioactive seco-rosane diterpenoid from Vellozia candida.

  title={A bioactive seco-rosane diterpenoid from Vellozia candida.},
  author={L. M. Valente and A. A. Gunatilaka and D. Kingston and M. Patitucci and A. C. Pinto},
  journal={Journal of natural products},
  volume={60 5},
  • L. M. Valente, A. A. Gunatilaka, +2 authors A. C. Pinto
  • Published 1997
  • Biology, Medicine
  • Journal of natural products
  • Bioassay-directed fractionation of the bioactive alcoholic extracts of Vellozia candida yielded a new 6,7-seco-rosane diterpenoid, candidalactone (1), which showed moderate toxicity toward DNA repair-deficient mutants of Saccharomyces cerevisiae. Another new but inactive rosane diterpenoid, candidenodiol (3), was also obtained. 
    4 Citations