A bioactive seco-rosane diterpenoid from Vellozia candida.
@article{Valente1997ABS,
title={A bioactive seco-rosane diterpenoid from Vellozia candida.},
author={L. M. Valente and A. A. Gunatilaka and D. Kingston and M. Patitucci and A. C. Pinto},
journal={Journal of natural products},
year={1997},
volume={60 5},
pages={
478-81
}
}Bioassay-directed fractionation of the bioactive alcoholic extracts of Vellozia candida yielded a new 6,7-seco-rosane diterpenoid, candidalactone (1), which showed moderate toxicity toward DNA repair-deficient mutants of Saccharomyces cerevisiae. Another new but inactive rosane diterpenoid, candidenodiol (3), was also obtained.
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