A benchmarked protein microarray-based platform for the identification of novel low-affinity extracellular protein interactions

Low-affinity extracellular protein interactions are critical for cellular recognition processes, but existing methods to detect them are limited in scale, making genome-wide interaction screens technically challenging. To address this, we report here the miniaturization of the AVEXIS (avidity-based extracellular interaction screen) assay by using protein… CONTINUE READING