A behavioral screen for isolating zebrafish mutants with visual system defects.

@article{Brockerhoff1995ABS,
  title={A behavioral screen for isolating zebrafish mutants with visual system defects.},
  author={Susan E Brockerhoff and James B Hurley and Ulrike Janssen-Bienhold and Stephan C F Neuhauss and Wolfgang Driever and John E. Dowling},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1995},
  volume={92 23},
  pages={10545-9}
}
Optokinetic and phototactic behaviors of zebrafish larvae were examined for their usefulness in screening for recessive defects in the visual system. The optokinetic response can be reliably and rapidly detected in 5-day larvae, whereas the phototactic response of larvae is variable and not robust enough to be useful for screening. We therefore measured optokinetic responses of mutagenized larvae as a genetic screen for visual system defects. Third-generation larvae, representing 266… CONTINUE READING
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