A basis set of de novo coiled-coil peptide oligomers for rational protein design and synthetic biology.

@article{Fletcher2012ABS,
  title={A basis set of de novo coiled-coil peptide oligomers for rational protein design and synthetic biology.},
  author={Jordan Fletcher and Aimee L Boyle and Marc Bruning and Gail J. Bartlett and Thomas L. Vincent and Nathan R. Zaccai and Craig T. Armstrong and Elizabeth H C Bromley and Paula Booth and R. Leo Brady and Andrew R. Thomson and Derek N. Woolfson},
  journal={ACS synthetic biology},
  year={2012},
  volume={1 6},
  pages={240-50}
}
Protein engineering, chemical biology, and synthetic biology would benefit from toolkits of peptide and protein components that could be exchanged reliably between systems while maintaining their structural and functional integrity. Ideally, such components should be highly defined and predictable in all respects of sequence, structure, stability, interactions, and function. To establish one such toolkit, here we present a basis set of de novo designed α-helical coiled-coil peptides that adopt… CONTINUE READING
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