A bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycle.


Pathogenic bacteria deliver effector proteins into host cells through the type III secretion apparatus to modulate the host function. We identify a family of proteins, homologous to the type III effector Cif from enteropathogenic Escherichia coli, in pathogens including Yersinia, Photorhabdus, and Burkholderia that contain functional type III secretion… (More)
DOI: 10.1073/pnas.0900212106


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