Crystal Structures of Cif from Bacterial Pathogens Photorhabdus luminescens and Burkholderia pseudomallei
- Allister Crow, Paul R. Race, +4 authors Mark J. Banfield
- PloS one
- 2009
Highly Influenced
7 Excerpts
A bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycle.
- Published 2009 in Proceedings of the National Academy of Sciences…
Abstract
Pathogenic bacteria deliver effector proteins into host cells through the type III secretion apparatus to modulate the host function. We identify a family of proteins, homologous to the type III effector Cif from enteropathogenic Escherichia coli, in pathogens including Yersinia, Photorhabdus, and Burkholderia that contain functional type III secretion… (More)