A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals

@inproceedings{Alegado2012ABS,
  title={A bacterial sulfonolipid triggers multicellular development in the closest living relatives of animals},
  author={Rosanna A. Alegado and Laura Brown and Shugeng Cao and Renee K Dermenjian and Richard Zuzow and Stephen Robert Fairclough and Jon Clardy and Nicole King},
  booktitle={eLife},
  year={2012}
}
Bacterially-produced small molecules exert profound influences on animal health, morphogenesis, and evolution through poorly understood mechanisms. In one of the closest living relatives of animals, the choanoflagellate Salpingoeca rosetta, we find that rosette colony development is induced by the prey bacterium Algoriphagus machipongonensis and its close relatives in the Bacteroidetes phylum. Here we show that a rosette inducing factor (RIF-1) produced by A. machipongonensis belongs to the… CONTINUE READING
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