A bacterial calcium-binding protein homologous to calmodulin

  title={A bacterial calcium-binding protein homologous to calmodulin},
  author={David G. Swan and Richard S. Hale and Namrita Dhillon and Peter Francis Leadlay},
Many of the effects of calcium ions in eukaryotic cells are mediated by calcium-binding regulatory proteins such as calmodulin, in which each calcium-binding site has a distinctive helix–loop–helix conformation termed the EF hand1,2. Protein S from the spore coat of the Gram-negative bacterium Myxococcus xanthus has been shown to resemble calmodulin in its internally-duplicated structure and ability to bind calcium3. However, it has a β-sheet secondary structure4,5 rather than the helix–loop… CONTINUE READING

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