A- and B-type lamins are differentially expressed in normal human tissues

@article{Broers1997AAB,
  title={A- and B-type lamins are differentially expressed in normal human tissues},
  author={Jos L. V. Broers and Barbie M. Machiels and Helma J. H. Kuijpers and Frank M M Smedts and Ronald van den Kieboom and Yves Raymond and Frans Charles Servatius Ramaekers},
  journal={Histochemistry and Cell Biology},
  year={1997},
  volume={107},
  pages={505-517}
}
 A selection of normal human tissues was investigated for the presence of lamins B1, B2, and A-type lamins, using a panel of antibodies specific for the individual lamin subtypes. By use of immunoprecipitation and two-dimensional immunoblotting techniques we demonstrated that these antibodies do not cross-react with other lamin subtypes and that a range of different phosphorylation isoforms is recognized by each antibody. The lamin B2 antibodies appeared to decorate the nuclear lamina in all… CONTINUE READING
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