A Whole-Cell Computational Model Predicts Phenotype from Genotype


Understanding how complex phenotypes arise from individual molecules and their interactions is a primary challenge in biology that computational approaches are poised to tackle. We report a whole-cell computational model of the life cycle of the human pathogen Mycoplasma genitalium that includes all of its molecular components and their interactions. An… (More)
DOI: 10.1016/j.cell.2012.05.044


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