A West Nile virus (WNV) recombinant canarypox virus vaccine elicits WNV-specific neutralizing antibodies and cell-mediated immune responses in the horse.

@article{Garch2008AWN,
  title={A West Nile virus (WNV) recombinant canarypox virus vaccine elicits WNV-specific neutralizing antibodies and cell-mediated immune responses in the horse.},
  author={Hanane El Garch and Jules Maarten Minke and Jussara Rehder and Sylvain Richard and C Edlund Toulemonde and Sonia Dinic and Christine Andr{\'e}oni and Jean Christophe Audonnet and Robert M Nordgren and V{\'e}ronique Juillard},
  journal={Veterinary immunology and immunopathology},
  year={2008},
  volume={123 3-4},
  pages={230-9}
}
Successful vaccination against West Nile virus (WNV) requires induction of both neutralizing antibodies and cell-mediated immune responses. In this study, we have assessed the ability of a recombinant ALVAC-WNV vaccine (RECOMBITEK WNV) to elicit neutralizing antibodies and virus-specific cell-mediated immune responses in horses. In addition, we examined whether prior exposure to ALVAC-WNV vaccine would inhibit B and cell-mediated immune responses against the transgene product upon subsequent… CONTINUE READING
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