A Voxel-Based Method for the Statistical Analysis of Gray and White Matter Density Applied to Schizophrenia

  title={A Voxel-Based Method for the Statistical Analysis of Gray and White Matter Density Applied to Schizophrenia},
  author={Ian C. Wright and Philip K. McGuire and J B Poline and J. M. Travere and Karl J. Friston},
We describe a novel technique for characterizing regional cerebral gray and white matter differences in structural magnetic resonance images by the application of methods derived from functional imaging. The technique involves automatic scalp-editing of images followed by segmentation, smoothing, and spatial normalization to a symmetrical template brain in stereotactic Talairach space. The basic idea is (i) to convert structural magnetic resonance image data into spatially normalized images of… 

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