A Validated Method without Derivatization for the Determination of Gabapentin in Bulk, Pharmaceutical Formulation and Human Urine Samples

@inproceedings{Gujral2009AVM,
  title={A Validated Method without Derivatization for the Determination of Gabapentin in Bulk, Pharmaceutical Formulation and Human Urine Samples},
  author={Rajinder Singh Gujral and S. K. Manirul Haque},
  booktitle={International journal of biomedical science : IJBS},
  year={2009}
}
A rapid, sensitive and accurate high performance liquid chromatography with UV detection method was developed and validated for the quantification of gabapentin in bulk, pharmaceutical formulation and human urine samples. Most of the published methods for analysis of gabapentin used derivatization with reagent. The present paper however describes the analysis of gabapentin without any derivatization. The chromatographic separation was carried out on a Waters C18 5 μm column (150 mm × 4.6 mm… CONTINUE READING