A Uve1p-mediated mismatch repair pathway in Schizosaccharomyces pombe.

@article{Kaur1999AUM,
  title={A Uve1p-mediated mismatch repair pathway in Schizosaccharomyces pombe.},
  author={Balwant Kaur and Jean L. Fraser and Greg A. Freyer and Scott Davey and Paul W Doetsch},
  journal={Molecular and cellular biology},
  year={1999},
  volume={19 7},
  pages={
          4703-10
        }
}
  • Balwant Kaur, Jean L. Fraser, +2 authors Paul W Doetsch
  • Published in
    Molecular and cellular…
    1999
  • Biology, Medicine
  • UV damage endonuclease (Uve1p) from Schizosaccharomyces pombe was initially described as a DNA repair enzyme specific for the repair of UV light-induced photoproducts and proposed as the initial step in an alternative excision repair pathway. Here we present biochemical and genetic evidence demonstrating that Uve1p is also a mismatch repair endonuclease which recognizes and cleaves DNA 5' to the mispaired base in a strand-specific manner. The biochemical properties of the Uve1p-mediated… CONTINUE READING

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