A Universal System for Highly Efficient Cardiac Differentiation of Human Induced Pluripotent Stem Cells That Eliminates Interline Variability

@inproceedings{Burridge2011AUS,
  title={A Universal System for Highly Efficient Cardiac Differentiation of
                    Human Induced Pluripotent Stem Cells That Eliminates Interline
                    Variability},
  author={Paul W. Burridge and Susan Thompson and Michal A. Millrod and Seth Weinberg and Xuan Yuan and Ann H. Peters and Vasiliki Mahairaki and Vassilis E. Koliatsos and Leslie Tung and Elias T. Zambidis},
  booktitle={PloS one},
  year={2011}
}
BACKGROUND The production of cardiomyocytes from human induced pluripotent stem cells (hiPSC) holds great promise for patient-specific cardiotoxicity drug testing, disease modeling, and cardiac regeneration. However, existing protocols for the differentiation of hiPSC to the cardiac lineage are inefficient and highly variable. We describe a highly efficient system for differentiation of human embryonic stem cells (hESC) and hiPSC to the cardiac lineage. This system eliminated the variability in… CONTINUE READING
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Generation of nonviral integration-free induced pluripotent stem cells from plucked human hair follicles

  • A Peters, E Zambidis
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