A United States survey on diagnosis, treatment, and outcome of primary hyperoxaluria

@article{Hoppe2003AUS,
  title={A United States survey on diagnosis, treatment, and outcome of primary hyperoxaluria},
  author={Bernd Hoppe and Craig B. Langman},
  journal={Pediatric Nephrology},
  year={2003},
  volume={18},
  pages={986-991}
}
Primary hyperoxaluria (PH) is a heterogeneous disease with a variable age of onset and a variable progression into kidney failure. Early diagnosis is mandatory to avoid the damaging effects of systemic calcium oxalate deposition. In 1997, we initiated a nationwide survey of American nephrologists to ascertain epidemiological data and current practices. PH was reported in only 102 patients, with PH I in 79 and PH II in 9; 14 patients were not classified. Most patients were Caucasian (84%). Main… 
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TLDR
In patients with a history of nephrocalcinosis and/or recurrent nephrolithiasis with progression to chronic kidney disease, this diagnosis should be excluded, especially before considering an isolated kidney transplant.
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TLDR
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TLDR
Patients' outcomes are improved when prolonged periods on dialysis and the complications of systemic oxalosis have not occurred and the results of 127 liver transplants performed in 117 patients over a 20-year period from 1984 to 2004 are described.
Late-onset primary hyperoxaluria diagnosed after renal transplantation presented with early recurrence of disease.
  • Hyeon-Hoe Kim, H. Koh, B. Ku, Hyun Soon Lee
  • Medicine, Biology
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
  • 2005
TLDR
A case of late-onset PH-I is reported, with the diagnosis being made only after transplantation presented with rapid intratubular calcium oxalate crystal deposition in a renal graft.
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