A Unique Chromosomal Rearrangement in the Cryptococcus neoformans var. grubii Type Strain Enhances Key Phenotypes Associated with Virulence

@article{Morrow2012AUC,
  title={A Unique Chromosomal Rearrangement in the Cryptococcus neoformans var. grubii Type Strain Enhances Key Phenotypes Associated with Virulence},
  author={Carl A. Morrow and I. Russel Lee and Eve W L Chow and Kate L Ormerod and Anita Goldinger and Edmond J. Byrnes and Kirsten Nielsen and Joseph Heitman and Horst Joachim Schirra and James Angus Fraser},
  journal={mBio},
  year={2012},
  volume={3}
}
ABSTRACT The accumulation of genomic structural variation between closely related populations over time can lead to reproductive isolation and speciation. The fungal pathogen Cryptococcus is thought to have recently diversified, forming a species complex containing members with distinct morphologies, distributions, and pathologies of infection. We have investigated structural changes in genomic architecture such as inversions and translocations that distinguish the most pathogenic variety… 
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