A Twist Opening Model for DNA

@article{Barbi1999ATO,
  title={A Twist Opening Model for DNA},
  author={Mauricio Barbi and Susanna Cocco and Michel Peyrard and Stefano Ruffo},
  journal={Journal of Biological Physics},
  year={1999},
  volume={24},
  pages={97-114}
}
The real mechanisms of several biological processes involving DNA are not yet understood. We discuss here some aspects of the initiation of transcription, in particular the formation of the open complex and the activation mechanism associated to enhancer binding proteins. Transcription activation seems to be governed by underlying dynamical mechanisms related to several distortions of the double chain structure: a dynamical approach on a mesoscopic description level could then allow a deeper… CONTINUE READING

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