A Tunable Protein Piston That Breaks Membranes to Release Encapsulated Cargo.


Movement of molecules across membranes in response to a stimulus is a key component of cellular programming. Here, we characterize and manipulate the response of a protein-based piston capable of puncturing membranes in a pH-dependent manner. Our protein actuator consists of modified R bodies found in a bacterial endosymbiont of paramecium. We express and… (More)
DOI: 10.1021/acssynbio.5b00237


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