A Tribute to Jean Hamburger's Contribution to Organ Transplantation

  title={A Tribute to Jean Hamburger's Contribution to Organ Transplantation},
  author={Christophe Legendre and Henri Kreis},
  journal={American Journal of Transplantation},
Jean Hamburger, one of the pioneers of scientific medicine in the mid‐20th century, who was involved in the inception of intensive care, nephrology, hemodialysis and scientific clinical research, has also been one of the very few fathers of human organ transplantation. He was involved in the primary French kidney transplantations in 1950, and in 1952, he realized the first allotransplantation in the world of a kidney removed from a voluntary living donor. At the same time, he was the first to… 
[The history of kidney transplantation].
The history of kidney transplantation is a history of many unsuccessful efforts and setbacks, but also the history of perseverance, pioneering spirit, and steadfast courage. The first successful
The history of kidney transplantation: Past,Present and Future
The Belgian example and all its historical measures could help others to fight against organ shortage and its consequences, organ trafficking, commercialization and tourism.
The History of Kidney Transplantation: Past, Present and Future (with Special References to the Belgian History)
The Belgian example and all its historical measures could help others to fight against organ shortage and its consequences, organ trafficking, commercialization and tourism.
Počeci transplantacije bubrega u Rijeci i Hrvatskoj – sjećanje jednog sudionika
During many years the authors performed more transplants from living donor due to pressure of many patients from other *Dopisni autor: Prof. Vinko Frančišković.
The First Transplant Kidney Biopsy Ever Performed
  • H. KreisL. NoëlC. Legendre
  • Medicine
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
  • 2013
This transplant was performed in emergency because the recipient’s congenitally single kidney had to be removed to keep under control a posttrauma hemorrhage. The transplanted kidney functioned well
Adding Another Voice to the Living Donor Kidney Transplant Discussions at the CIBA Symposium of 1966
Two qualitative interviews with men who donated at different centers in the United States in the early 1960s and subsequently developed end-stage renal disease (ESRD) contribute to five topics discussed at the CIBA meeting that are still relevant today.
Transplantation tolerance; myth or reality?
The only answer to this problem is "Transplant tolerance" which means stable allograft function while maintaining third party immune response intact in absence of rejections on no immunosuppression.
Evaluation of Immunosuppressive Activity of Demethylzeylasteral in a Beagle Dog Kidney Transplantation Model
It is demonstrated that T- 96 can inhibit acute rejection in kidney transplantation, and the inhibitory effect of T-96 was enhanced when combined with CsA, which suggests the possible use in organ transplantation to prevent immune rejection.
Clinical and immunological features of very long‐term survivors with a single renal transplant
  • L. BererhiN. Pallet S. Candon
  • Medicine, Biology
    Transplant international : official journal of the European Society for Organ Transplantation
  • 2012
The results suggest that the impact of chronic immunosuppression on some immune functions does not worsen over time and that the observed high prevalence of cancer in these patients may be related to the synergistic effects of decreased immunosurveillance and the time required for carcinogenesis.
Very long‐term follow‐up of living kidney donors
Living kidney donation does not impact survival, kidney function, medical condition or psychological or social status over the very long‐term.


Successful Homotransplantation of the Kidney between Nonidentical Twins
The purpose of this paper is to report the functional survival of a transplanted kidney whose donor was a fraternal, not an identical, twin.
Inhibition of the rejection of renal homografts in dogs by drugs.
Of the various methods of preventing renal homograft rejection discussed, thiopurine drugs appear to be the only agents that have a repeatable effect on adult animals and the lethal effect of irradiation above 1300 r precludes the use of such a dose clinically.
The Immunological Follow up of Renal Allograft Recipients
  • J. Hamburger
  • Medicine, Biology
    Proceedings of the Royal Society of Medicine
  • 1972
The chief purpose of this lecture is to discuss whether it is possible to follow up patients, not only on a clinical basis, but also with a regular evaluation of their immunological state with five main tests: the search for transformed lymphocytes in vivo, the mixed lymphocyte culture, the leukocyte migration inhibition test, the rosette test and the colony inhibition test.
[Insulin-dependent diabetes, an autoimmune disease].
  • J. Hamburger
  • Biology, Medicine
    Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie
  • 1986
In type I (insulin-dependent) diabetes evidence for an autoimmune process is now fully established and T-lymphocyte mediated cellular immunity is demonstrated in both these diabetic animals and in the human.
Une tentative de transplantation rénale chez l’homme: aspects médicaux et biologiques
  • Presse Méd
  • 1953
Quelques essais de greffes de rein chez l’homme
  • Mem Acad Chir (France)
  • 1951
[How to conduct a clinical therapeutic trial].
Transplantation reactions in humans.