A Tissue Displacement-based Contusive Spinal Cord Injury Model in Mice

@inproceedings{Wu2017ATD,
  title={A Tissue Displacement-based Contusive Spinal Cord Injury Model in Mice},
  author={Xiangbing Wu and Yi Zhang and Wenrui Qu and Lisa B. E. Shields and Christopher B Shields and Xiao-Ming Xu},
  booktitle={Journal of visualized experiments : JoVE},
  year={2017}
}
Producing a consistent and reproducible contusive spinal cord injury (SCI) is critical to minimizing behavioral and histological variabilities between experimental animals. Several contusive SCI models have been developed to produce injuries using different mechanisms. The severity of the SCI is based on the height that a given weight is dropped, the injury force, or the spinal cord displacement. In the current study, we introduce a novel mouse contusive SCI device, the Louisville Injury System… CONTINUE READING

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