A Throat Lozenge Containing Amyl Meta Cresol and Dichlorobenzyl Alcohol Has a Direct Virucidal Effect on Respiratory Syncytial Virus, Influenza a and SARS-CoV

@article{Oxford2005ATL,
  title={A Throat Lozenge Containing Amyl Meta Cresol and Dichlorobenzyl Alcohol Has a Direct Virucidal Effect on Respiratory Syncytial Virus, Influenza a and SARS-CoV},
  author={J. Oxford and R. Lambkin and I. Gibb and S. Balasingam and Charlotte Chan and A. Catchpole},
  journal={Antiviral Chemistry and Chemotherapy},
  year={2005},
  volume={16},
  pages={129 - 134}
}
  • J. Oxford, R. Lambkin, +3 authors A. Catchpole
  • Published 2005
  • Biology, Medicine
  • Antiviral Chemistry and Chemotherapy
  • A potent virucidal mixture containing amyl metacresol and dichlorobenzyl alcohol at low pH inactivated enveloped respiratory viruses influenza A, respiratory synctial virus (RSV) and severe acute respiratory syndrome coronavirus (SARS-CoV) but not viruses with icosahedral symmetry, such as adenoviruses or rhinoviruses. A titre of approximately 3.5 log10 TCID50 was reduced to below the level of detection within two minutes. Electron microscopy of purified influenza A virus showed extensive… CONTINUE READING
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