A Th0/Th2-like function of CD4+CD7- T helper cells from normal donors and HIV-infected patients.

@article{Autran1995ATF,
  title={A Th0/Th2-like function of CD4+CD7- T helper cells from normal donors and HIV-infected patients.},
  author={Brigitte Autran and {\'E}ric Legac and Catherine Blanc and Patrice Debr{\'e}},
  journal={Journal of immunology},
  year={1995},
  volume={154 3},
  pages={1408-17}
}
We previously reported the expansion during HIV infection of a subset of CD4+ T cells characterized by a lack of CD7 cell surface expression. This CD4+CD7- subset showed in normal donors a lower cell proliferation than CD4+CD7+ autologous cells after CD3 triggering or CD28 costimulation. Our aim was to further characterize the Th function of this CD4+CD7- T cell subset, both in normal donors and in HIV-infected patients. Their CD4+CD7- cell proliferation and cytokine secretion were analyzed… CONTINUE READING

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