A Targeted Proteomics Analysis of Cerebrospinal Fluid after Acute Human Spinal Cord Injury.

@article{Streijger2017ATP,
  title={A Targeted Proteomics Analysis of Cerebrospinal Fluid after Acute Human Spinal Cord Injury.},
  author={Femke Streijger and Michael A. Skinnider and Jason C. Rogalski and Robert F Balshaw and Casey P. Shannon and Anna Prudova and Lise M.A. B{\'e}langer and Leanna Ritchie and Angela Tsang and Sean D Christie and Stefan Parent and Jean-Marc Mac-Thiong and Christopher Bailey and Jennifer C. Urquhart and T Ailon and Scott J Paquette and Michael C. Boyd and John T. Street and Charles G Fisher and Marcel F. Dvorak and Christoph H. Borchers and Leonard J. Foster and Brian K Kwon},
  journal={Journal of neurotrauma},
  year={2017},
  volume={34 12},
  pages={
          2054-2068
        }
}
Efforts to validate novel therapies in acute clinical trials for spinal cord injury (SCI) are impeded by the lack of objective quantitative measures that reflect injury severity and accurately predict neurological recovery. Therefore, a strong rationale exists for establishing neurochemical biomarkers that objectively quantify injury severity and predict outcome. Here, we conducted a targeted proteomics analysis of cerebrospinal fluid (CSF) samples derived from 29 acute SCI patients (American… CONTINUE READING
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