A TPGS-incorporating nanoemulsion of paclitaxel circumvents drug resistance in breast cancer.

@article{Bu2014ATN,
  title={A TPGS-incorporating nanoemulsion of paclitaxel circumvents drug resistance in breast cancer.},
  author={Huihui Bu and Xinyu He and Zhiwen Zhang and Qi Yin and Yaping Li},
  journal={International journal of pharmaceutics},
  year={2014},
  volume={471 1-2},
  pages={206-13}
}
Paclitaxel resistance is usually developed in clinical chemotherapy, which remains a major obstacle for successful cancer treatment. Herein, we attempted to develop a TPGS incorporating nanoemulsion of paclitaxel (NE-PTX) to circumvent the drug resistance in breast cancer. NE-PTX was prepared by a self-assembly technique and the physicochemical properties were characterized. The efficacy of NE-PTX on overcoming paclitaxel resistance was measured by in vitro and in vivo evaluation. The measured… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…