A T-bet gradient controls the fate and function of CCR6−RORγt+ innate lymphoid cells

@article{Klose2013ATG,
  title={A T-bet gradient controls the fate and function of CCR6−RORγt+ innate lymphoid cells},
  author={Christoph S. N. Klose and Elina A. Kiss and V. Schwierzeck and Karolina Ebert and Thomas Hoyler and Y. d’Hargues and Nathalie G{\"o}ppert and Andrew L Croxford and A. Waisman and Y. Tanriver and A. Diefenbach},
  journal={Nature},
  year={2013},
  volume={494},
  pages={261-265}
}
  • Christoph S. N. Klose, Elina A. Kiss, +8 authors A. Diefenbach
  • Published 2013
  • Medicine, Biology
  • Nature
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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 55 REFERENCES
    T-bet in disease
    195