A Systems Biology Approach to Infectious Disease Research: Innovating the Pathogen-Host Research Paradigm

@inproceedings{Aderem2011ASB,
  title={A Systems Biology Approach to Infectious Disease Research: Innovating the Pathogen-Host Research Paradigm},
  author={Alan Aderem and Joshua N. Adkins and Charles Ansong and James E. Galagan and Shari Kaiser and Marcus J. Korth and G. Lynn Law and Jason G. McDermott and Sean C. Proll and Carrie M. Rosenberger and Gary K. Schoolnik and Michael G. Katze},
  booktitle={mBio},
  year={2011}
}
The twentieth century was marked by extraordinary advances in our understanding of microbes and infectious disease, but pandemics remain, food and waterborne illnesses are frequent, multidrug-resistant microbes are on the rise, and the needed drugs and vaccines have not been developed. The scientific approaches of the past-including the intense focus on individual genes and proteins typical of molecular biology-have not been sufficient to address these challenges. The first decade of the twenty… CONTINUE READING

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