A Systematic Review of the Trace Element Concentrations in the Prostate Fluid of Normal Gland

@inproceedings{Zaichick2020ASR,
  title={A Systematic Review of the Trace Element Concentrations in the Prostate Fluid of Normal Gland},
  author={Vladimir Zaichick},
  year={2020}
}
Background: The prostate gland is subject to various disorders. The etiology and pathogenesis of these diseases are not well understood. Moreover, despite technological advancements, the differential diagnostics of prostate disorders has become progressively more complex and controversial. It was suggested that the measurement of Trace Elements (TEs) levels in Expressed Prostatic Fluid (EPF) may be useful as a biomarker. This suggestion promoted more detailed studies of the TEs concentrations… 

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References

SHOWING 1-10 OF 89 REFERENCES

Trace Elements of Expressed Prostatic Secretions as a Source for Biomarkers of Prostate Cancer

TLDR
The decrease in levels of Zn and Rb in the fluid of cancerous prostate might demonstrate involvement of these trace elements in etiology and pathogenesis of malignant prostate tumors.

Trace Element Concentrations in the Expressed Prostatic Secretion of Normal and Hyperplastic Prostate

  • V. Zaichick
  • Medicine
    Journal of Urology & Nephrology Studies
  • 2018
TLDR
The alterations in levels of Zn and Rb in the EPF of hyperplastic prostate might demonstrate an involvement of these trace elements in etiology and pathogenesis of BPH.

Significance of trace element quantities in the prostatic secretion of patients with benign prostatic hyperplasia and prostate cancer

TLDR
The great decrease in levels of Rb and Zn in the fluid of cancerous prostate might demonstrate an involvement of these trace elements in etiology and pathogenesis of malignant prostate tumors.

Br, Fe, Rb, Sr, and Zn Levels in the Prostatic Secretion of Patients with Chronic Prostatitis

Objective: Chronic prostatitis (CP) is an internationally important health problem of the man, particularly in developed countries. The aim of this exploratory study was to evaluate whether

Age-Related Changes in Concentration and Histological Distribution of 54 Trace Elements in Nonhyperplastic Prostate of Adults

TLDR
Evidence of a disturbance in prostatic trace element concentrations and their histological distribution was shown for ages above 40 years and it was demonstrated that the glandular lumen and, therefore, prostatic fluid is a main pool of Zn accumulation in the normal human prostate.

Some Trace Element Contents and Ratios in Prostatic Fluids as Ancillary Diagnostic Tools in Distinguishing between the Benign Prostatic Hyperplasia and Chronic Prostatitis

TLDR
Evaluated whether significant difference in the contents of Zn and some other trace elements as well as in the Zn/trace elements ratios of prostatic fluid exist between the inflamed and hyperplastic prostate and whether these can be used as markers in distinguishing between CP and BPH.

Intracellular Zinc Excess as One of the Main Factors in the Etiology of Prostate Cancer

TLDR
It is hypothesized that the prostatic intracellular Zn concentrations are probably one of the most important factors in the etiology of PCa and may disturb the cells’ functions, resulting in cellular degeneration, death or malignant transformation.

Trace Element Levels in Prostate Gland as Carcinoma’s Markers

TLDR
The Ag, Al, B, Br, Li, Mn, Ni, and Zn mass fraction in a needle-biopsy core can be used as the informative indicators for distinguishing malignant from benign prostate.

The effect of chronic prostatitis on zinc concentration of prostatic fluid and seminal plasma: a systematic review and meta-analysis

TLDR
There was a significant negative effect of chronic prostatitis on zinc concentrations of prostatic fluid and seminal plasma, and further studies with larger sample sizes are needed to better illuminate the negative impact.

The Distribution of 54 Trace Elements Including Zinc in Pediatric and Nonhyperplastic Young Adult Prostate Gland Tissues

The distribution of Zn and other trace elements in prostate tissues provide information that can be key to better understanding of physiological and biochemical functions of prostate gland. For this
...