A Systematic Review of Prostatic Artery Embolization in the Treatment of Symptomatic Benign Prostatic Hyperplasia

@article{Kuang2016ASR,
  title={A Systematic Review of Prostatic Artery Embolization in the Treatment of Symptomatic Benign Prostatic Hyperplasia},
  author={M. Kuang and Anthony Vu and Sriharsha Athreya},
  journal={CardioVascular and Interventional Radiology},
  year={2016},
  volume={40},
  pages={655-663}
}
PurposeTo summarize current evidence on outcomes and complications of prostatic artery embolization as a treatment for patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia.Methods and MaterialsA database search of MEDLINE, Embase, Web of Science, and Cochrane Library was performed for published literature up to August 2015 concerning PAE in the treatment of BPH. Inclusion and exclusion criteria were applied by two independent reviewers, and disagreements were… 
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43 Citations
Highly Influential Citations
1
Background Citations
9
Methods Citations
2
Results Citations
2

43 Citations

Prostatic arterial embolization for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia.
TLDR
The comparison of PAE versus TURP is the primary topic of interest and very uncertain about the effects on erectile function and low-certainty evidence is found.
Prostatic arterial embolization for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia.
TLDR
Prostatic arterial embolization may make little to no difference in erectile function measured by the International Index of Erectile Function-5 on a scale from 1 to 25, with higher scores indicating better function and lower scores indicating worse symptoms, according to the Cochrane Handbook for Systematic Reviews of Interventions.
Prostate artery embolisation for benign prostatic hyperplasia: a systematic review and meta-analysis
TLDR
It is suggested that PAE can reduce moderate to severe LUTS in men with BPH with a low risk of complications and use of cone-beam CT may reduce risk of non-target embolisation.
Prostatic Artery Embolization for the Treatment of Benign Prostate Hyperplasia: Initial Experience From Bahrain
TLDR
Prostatic artery embolization is a minimally invasive procedure that is safe and effective for the management of BPH and is effective forThe management of both storage and voiding symptoms.
Embolisation of prostate arteries in benign prostatic hyperplasia in non-surgical patients
Prostatic artery embolization for benign prostatic hyperplasia: a review
TLDR
Initial data on PAE shows it can provide excellent clinical outcomes with patients experiencing minimal complications, however, more high-quality, high-level data are needed particularly in regards to long-term outcomes to determine durability.
Penile Glans Necrosis Following Prostatic Artery Embolization for Benign Prostatic Hyperplasia: Case Series and Review of Current Literature.
  • E. Chung
  • Medicine
    The world journal of men's health
  • 2022
TLDR
HBOT appears to expedite the recovery process in men with PGN related to PAE with better erection scores compared to conservative measure, including the emerging role of hyperbaric oxygen therapy (HBOT) for PGN.
Prostate Artery Embolization in Patients above Eighty Years Old: Clinical Efficacy and Safety
TLDR
Prostate artery embolization is a feasible low-risk treatment for LUTS with or without urinary retention or prostatic hematuria in elderly patients and succeeds in stopping bleeding in 16 out of 17 patients with prostate-induced Hematuria.
Prostatic Artery Embolization for Benign Prostatic Obstruction: Single-Centre Retrospective Study Comparing Microspheres Versus n-Butyl Cyanoacrylate
TLDR
PAE using NBCA was safe and effective for symptomatic BPO, with faster procedures, lower radiation exposure and similar safety and efficacy compared to microspheres, and operator learning curve could have biased the procedural times and radiation exposure between groups favouring NBCA.
Systematic Review and Meta-analysis Comparing Prostatic Artery Embolization to Gold-Standard Transurethral Resection of the Prostate for Benign Prostatic Hyperplasia
TLDR
While TURP demonstrated larger improvements for some objective parameters, PAE was associated with fewer AEs and shorter hospitalization times, and subjective symptom improvement was equivalent between TURp and PAE.
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References

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Early results from a United States trial of prostatic artery embolization in the treatment of benign prostatic hyperplasia.
Unilateral Versus Bilateral Prostatic Arterial Embolization for Lower Urinary Tract Symptoms in Patients with Prostate Enlargement
TLDR
PAE is a safe and effective technique that can induce 48 % improvement in the IPSS score and a prostate volume reduction of 19 %, with good clinical outcome in up to 75 % of treated patients.
Benign prostatic hyperplasia: prostatic arterial embolization versus transurethral resection of the prostate--a prospective, randomized, and controlled clinical trial.
TLDR
Both procedures resulted in significant clinical improvements in the treatment of BPH, however, the advantages of the PAE procedure must be weighed against the potential for technical and clinical failures in a minority of patients.
Prostatic artery embolization for treatment of benign prostatic hyperplasia in patients with prostates > 90 g: a prospective single-center study.
Embolisation of prostatic arteries as treatment of moderate to severe lower urinary symptoms (LUTS) secondary to benign hyperplasia: results of short- and mid-term follow-up
TLDR
PAE is a procedure with good results for BPH patients with moderate to severe lower urinary tract symptoms after failure of medical treatment for at least 6 months, and is a promising new technique that has shown good results.
Prostatic arterial embolization for the treatment of lower urinary tract symptoms due to large (>80 mL) benign prostatic hyperplasia: results of midterm follow-up from Chinese population
TLDR
PAE is a safe and effective treatment method for patients with lower urinary tract symptoms (LUTS) due to large volume BPH and may play an important role in patients in whom medical therapy has failed, who are not candidates for open surgery or TURP or refuse any surgical treatment.
Prostatic artery embolization for prostate volume greater than 80 cm3: results from a single-center prospective study.
Quality of life and clinical symptom improvement support prostatic artery embolization for patients with acute urinary retention caused by benign prostatic hyperplasia.
Prostatic Arterial Embolization with Small Sized Particles for the Treatment of Lower Urinary Tract Symptoms Due to Large Benign Prostatic Hyperplasia: Preliminary Results
TLDR
The combination of 50 &mgr;m and 100 &mGr;m particles for PAE is a safe and effective treatment method for patients with severe LUTS due to large BPH, which further improves the clinical results of PAE.
A Systematic Review and Meta-analysis of Functional Outcomes and Complications Following Transurethral Procedures for Lower Urinary Tract Symptoms Resulting from Benign Prostatic Obstruction: An Update.
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