A Systematic Review of Intraoperative Radiotherapy in Early Breast Cancer

  title={A Systematic Review of Intraoperative Radiotherapy in Early Breast Cancer},
  author={Astrid V Cuncins-Hearn and Christobel Saunders and David Walsh and Martin Borg and John M Buckingham and Frank A Frizelle and Guy J Maddern},
  journal={Breast Cancer Research and Treatment},
A systematic review was undertaken to assess the safety and efficacy of intraoperative radiotherapy (IORT) in early breast cancer compared with breast conserving surgery with postoperative radiotherapy. Literature databases were searched up to March 2002 inclusive. IORT studies of any design and breast conserving therapy randomised controlled trials with sample sizes greater than 500 patients (with at least one arm of breast conserving therapy (BCT)) and systematic reviews on BCT published… CONTINUE READING


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