A Systematic Review and Meta-Analysis of the Risk of Dementia Associated with Benzodiazepine Use, After Controlling for Protopathic Bias

@article{Penninkilampi2018ASR,
  title={A Systematic Review and Meta-Analysis of the Risk of Dementia Associated with Benzodiazepine Use, After Controlling for Protopathic Bias},
  author={R. Penninkilampi and G. Eslick},
  journal={CNS Drugs},
  year={2018},
  volume={32},
  pages={485-497}
}
BackgroundBenzodiazepine use is highly prevalent in elderly and late middle-aged populations and may be associated with an increased risk of dementia. Observational studies have suggested that benzodiazepine use may increase the risk of dementia, however there have been significant concerns regarding protopathic bias in these studies, precluding conclusive findings.ObjectiveThe aim of our study was to investigate the risk of dementia associated with the use of benzodiazepines in elderly… Expand
25 Citations
Association between Anxiety and Vascular Dementia Risk: New Evidence and an Updated Meta-Analysis
  • 1
  • PDF
Neuropathological Correlates of Cumulative Benzodiazepine and Anticholinergic Drug Use.
  • PDF
Intake of Meat, Fish, Fruits, and Vegetables and Long-Term Risk of Dementia and Alzheimer's Disease.
  • 2
  • PDF
...
1
2
3
...

References

SHOWING 1-10 OF 59 REFERENCES
Benzodiazepine Use and Risk of Dementia in the Elderly Population: A Systematic Review and Meta-Analysis
  • 86
Association between Benzodiazepine Use and Dementia: A Meta-Analysis
  • 78
  • PDF
Is there really a link between benzodiazepine use and the risk of dementia?
  • 67
Benzodiazepine use and risk of dementia: prospective population based study
  • 342
  • PDF
Benzodiazepine use and risk of dementia: a nested case-control study.
  • 128
  • PDF
Benzodiazepine Use and Risk of Developing Alzheimer’s Disease or Vascular Dementia: A Case–Control Analysis
  • 58
  • Highly Influential
  • PDF
Benzodiazepine use and risk of dementia: evidence from the Caerphilly Prospective Study (CaPS)
  • 103
Effect of benzodiazepine discontinuation on dementia risk.
  • 76
Association between Benzodiazepine Use and Dementia: Data Mining of Different Medical Databases
  • 29
  • PDF
...
1
2
3
4
5
...