A Systematic Review and Meta-Analysis of the Risk of Dementia Associated with Benzodiazepine Use, After Controlling for Protopathic Bias

@article{Penninkilampi2018ASR,
  title={A Systematic Review and Meta-Analysis of the Risk of Dementia Associated with Benzodiazepine Use, After Controlling for Protopathic Bias},
  author={R. Penninkilampi and G. Eslick},
  journal={CNS Drugs},
  year={2018},
  volume={32},
  pages={485-497}
}
BackgroundBenzodiazepine use is highly prevalent in elderly and late middle-aged populations and may be associated with an increased risk of dementia. Observational studies have suggested that benzodiazepine use may increase the risk of dementia, however there have been significant concerns regarding protopathic bias in these studies, precluding conclusive findings.ObjectiveThe aim of our study was to investigate the risk of dementia associated with the use of benzodiazepines in elderly… Expand
View on Springer
ncbi.nlm.nih.gov
25 Citations
Background Citations
5

25 Citations

Citation Type

Citation Type

History of Benzodiazepine Prescriptions and Risk of Dementia: Possible Bias Due to Prevalent Users and Covariate Measurement Timing in a Nested Case-Control Study
  • 15
  • PDF
Does Anxiety Increase the Risk of all-Cause Dementia? An Updated Meta-Analysis of Prospective Cohort Studies
  • 3
  • PDF
Association between Anxiety and Vascular Dementia Risk: New Evidence and an Updated Meta-Analysis
  • 1
  • PDF
The Effects of Benzodiazepine Use and Abuse on Cognition in the Elders: A Systematic Review and Meta-Analysis of Comparative Studies
Impact of benzodiazepine consumption reduction on future burden of dementia
  • PDF
Association between concurrent antidepressant and hypnotic treatment and the risk of dementia: A nationwide cohort study.
Benzodiazepines and the Risk of Alzheimer's Disease: Association or Protopathic Bias?
  • PDF
Association between Development of Dementia and Use of Benzodiazepines: A Systematic Review and Meta‐Analysis
  • 18
Neuropathological Correlates of Cumulative Benzodiazepine and Anticholinergic Drug Use.
  • PDF
Intake of Meat, Fish, Fruits, and Vegetables and Long-Term Risk of Dementia and Alzheimer's Disease.
  • 2
  • PDF
...
1
2
3
...

References

SHOWING 1-10 OF 59 REFERENCES
Benzodiazepine Use and Risk of Dementia in the Elderly Population: A Systematic Review and Meta-Analysis
  • 86
Association between Benzodiazepine Use and Dementia: A Meta-Analysis
  • 78
  • PDF
Is there really a link between benzodiazepine use and the risk of dementia?
  • 67
Benzodiazepine use and risk of dementia: prospective population based study
  • 342
  • PDF
Is benzodiazepine use a risk factor for cognitive decline and dementia? A literature review of epidemiological studies
  • 96
Benzodiazepine use and risk of dementia: a nested case-control study.
  • 128
  • PDF
Benzodiazepine Use and Risk of Developing Alzheimer’s Disease or Vascular Dementia: A Case–Control Analysis
  • 58
  • Highly Influential
  • PDF
Benzodiazepine use and risk of dementia: evidence from the Caerphilly Prospective Study (CaPS)
  • 103
Effect of benzodiazepine discontinuation on dementia risk.
  • 76
Association between Benzodiazepine Use and Dementia: Data Mining of Different Medical Databases
  • 29
  • PDF
...
1
2
3
4
5
...