A Systematic Analysis of Cell Cycle Regulators in Yeast Reveals That Most Factors Act Independently of Cell Size to Control Initiation of Division

@inproceedings{Hoose2012ASA,
  title={A Systematic Analysis of Cell Cycle Regulators in Yeast Reveals That Most Factors Act Independently of Cell Size to Control Initiation of Division},
  author={Scott A. Hoose and Jeremy A. Rawlings and Michelle M. Kelly and Margaret Camille Leitch and Qotaiba O. Ababneh and Juan P. Robles and David Taylor and Evelyn M. Hoover and Bethel Hailu and Kayla Anne McEnery and S. Sabina Downing and Deepika Kaushal and Yi Chen and Alex Rife and Kirtan A. Brahmbhatt and Roger Smith and Michael Polymenis},
  booktitle={PLoS genetics},
  year={2012}
}
Upstream events that trigger initiation of cell division, at a point called START in yeast, determine the overall rates of cell proliferation. The identity and complete sequence of those events remain unknown. Previous studies relied mainly on cell size changes to identify systematically genes required for the timely completion of START. Here, we evaluated panels of non-essential single gene deletion strains for altered DNA content by flow cytometry. This analysis revealed that most gene… CONTINUE READING
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The BioGRID Interaction Database: 2011 update

  • C Stark, BJ Breitkreutz, A Chatr-Aryamontri, L Boucher, R Oughtred
  • Nucleic Acids Res
  • 2011
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