A Sympathomometic Pressor Substance in Animal Organ Extracts

  title={A Sympathomometic Pressor Substance in Animal Organ Extracts},
  author={Ulf S. von Euler},
DURING a quantitative study of the piperidine content of various animal organs, following the identification of this substance as a normal constituent of urine1, it was observed that most organs contain considerable amounts of a pressor substance different from piperidine. 
A Substance with Sympathin E Properties in Spleen Extracts
ALCOHOLIC extracts of fresh spleen from cattle contain high amounts, up to 10 µgm. adrenaline equivalents per gm. tissue, of a cardio-accelerator and blood-pressure raising substance, showing theExpand
An Undialysable Pressor Principle in Organ Extracts
IN an earlier1 communication the occurrence of an adrenaline-like pressor substance in ether extracts of various animal organs has been reported. The primary extracts were made with two volumes ofExpand
The Presence of a Substance with Sympathin E Properties in Spleen Extracts
Summary. 1  Extracts of fresh cattle spleen possess a pressor activity equivalent to some 10 μg adrenaline per g of tissue. 2  The purified substance increases the heart rate and raises theExpand
Sympathomimetic Substance in Human Lumbar Sympathetic Chain
It is shown that if a postganglionic sympathetic nerve was stimulated electrically, and the cut end of the nerve allowed to hang beneath the surface of acidified saline during the passage of the current, the saline assumed Sympathomimetic properties from diffusion into it of an adrenaline-like substance from the nerve. Expand
Depressor and Pressor Activity of Extracts from the Aortic Wall of Cattle.
Summary The depressor and pressor activity of extracts from the aortic walls of cattle have been investigated, using the extraction method described by Euler. The depressor action seems toExpand
  • L. Gunne
  • Medicine
  • Annals of the New York Academy of Sciences
  • 1962
A study of the catecholamine metabolism in rats given morphine in increasing doses for three weeks finds that these studies have been extended to include the metabolism of certain monoamines of current interest. Expand
The effect of noradrenaline on the survival of rats subjected to hemorrhagic shock.
Reports of the efficacy of l-noradrenaline in the treatment of clinical shock stimulated an investigation of its effect in controlled hemorrhagic hypotension. Seventy-three 350-g. male Sprague–DawleyExpand
Causes, consequences, and cures for neuroinflammation mediated via the locus coeruleus: noradrenergic signaling system
The anti‐inflammatory and neuroprotective actions of NA are summarized, examples of how LC damage worsens disease are summed up, and several approaches taken to treat or prevent reductions in NA levels and LC neuronal damage are discussed. Expand
Hæmoglobin in Blood-sucking Parasites
The hæmoglobins of a host and of its bloodsucking parasite will not be identical; the differences between them could be used as specific characters within a genus. Expand
Wounded brain, ailing heart: Central autonomic network disruption in acute stroke
The authors argue that the right anterior insular cortex is involved in the regulation of parasympathetic tone, citing the results of 2 recent quantitative meta-analyses, and suggest that vascular damage to right-sided dorsal anterior insula results in downregulation of parASYmpathetic activity. Expand


Identification of a Urine Base with Nicotine-like Action
IN a previous communication, the isolation from urine of a volatile base with nicotine-like action has been announced1. The active substance was obtained from normal fresh cow's urine by means ofExpand