A Sympathomometic Pressor Substance in Animal Organ Extracts

  title={A Sympathomometic Pressor Substance in Animal Organ Extracts},
  author={Ulf S. von Euler},
DURING a quantitative study of the piperidine content of various animal organs, following the identification of this substance as a normal constituent of urine1, it was observed that most organs contain considerable amounts of a pressor substance different from piperidine. 

A Substance with Sympathin E Properties in Spleen Extracts

The active substance in spleen conforms better with an amino-base, such as nor-adrenaline, than with adrenaline, and is found to differ from adrenaline in the following respects.

An Undialysable Pressor Principle in Organ Extracts

The content in the bags after dialysis showed a strong pressor action on the cat in chloralose anaesthesia, and the whole of the pressor activity became dialysable.

Sympathomimetic Substance in Human Lumbar Sympathetic Chain

It is shown that if a postganglionic sympathetic nerve was stimulated electrically, and the cut end of the nerve allowed to hang beneath the surface of acidified saline during the passage of the current, the saline assumed Sympathomimetic properties from diffusion into it of an adrenaline-like substance from the nerve.


  • L. Gunne
  • Medicine, Psychology
    Annals of the New York Academy of Sciences
  • 1962
A study of the catecholamine metabolism in rats given morphine in increasing doses for three weeks finds that these studies have been extended to include the metabolism of certain monoamines of current interest.

The effect of noradrenaline on the survival of rats subjected to hemorrhagic shock.

Reports of the efficacy of l-noradrenaline in the treatment of clinical shock stimulated an investigation of its effect in controlled hemorrhagic hypotension. Seventy-three 350-g. male Sprague–Dawley

Causes, consequences, and cures for neuroinflammation mediated via the locus coeruleus: noradrenergic signaling system

The anti‐inflammatory and neuroprotective actions of NA are summarized, examples of how LC damage worsens disease are summed up, and several approaches taken to treat or prevent reductions in NA levels and LC neuronal damage are discussed.

Hæmoglobin in Blood-sucking Parasites

The hæmoglobins of a host and of its bloodsucking parasite will not be identical; the differences between them could be used as specific characters within a genus.

Wounded brain, ailing heart: Central autonomic network disruption in acute stroke

The authors argue that the right anterior insular cortex is involved in the regulation of parasympathetic tone, citing the results of 2 recent quantitative meta-analyses, and suggest that vascular damage to right-sided dorsal anterior insula results in downregulation of parASYmpathetic activity.

New Approaches for Chemical Analysis of Single Cells and Vesicles

An electrochemical method called vesicle impact electrochemical cytometry (VIEC) is developed that allows direct quantification of the vesicular content in secretory granules as demonstrated with large dense-core granules from chromaffin and pheochromocytoma (PC12) cells.

Neurohormanal bedingte Herzkrankheiten (Pathogenese und Therapie)

Es wurden die krankhaften Zustände angeführt, bei denen Adrenalin and Sympathin in abnorm gesteigerten Mengen ins Blut and in the Herzmuskel entladen werden.


Identification of a Urine Base with Nicotine-like Action

IN a previous communication, the isolation from urine of a volatile base with nicotine-like action has been announced1. The active substance was obtained from normal fresh cow's urine by means of