A Sympathomometic Pressor Substance in Animal Organ Extracts

  title={A Sympathomometic Pressor Substance in Animal Organ Extracts},
  author={Ulf S. von Euler},
DURING a quantitative study of the piperidine content of various animal organs, following the identification of this substance as a normal constituent of urine1, it was observed that most organs contain considerable amounts of a pressor substance different from piperidine. 
An Undialysable Pressor Principle in Organ Extracts
The content in the bags after dialysis showed a strong pressor action on the cat in chloralose anaesthesia, and the whole of the pressor activity became dialysable.
The Presence of a Substance with Sympathin E Properties in Spleen Extracts
The similarity between the action of the purified spleen extracts and the postulated sympathin E on the one hand and nor-adrenaline or D. N. E. on the other is pointed out.
Sympathomimetic Substance in Human Lumbar Sympathetic Chain
It is shown that if a postganglionic sympathetic nerve was stimulated electrically, and the cut end of the nerve allowed to hang beneath the surface of acidified saline during the passage of the current, the saline assumed Sympathomimetic properties from diffusion into it of an adrenaline-like substance from the nerve.
Depressor and Pressor Activity of Extracts from the Aortic Wall of Cattle.
The depressor and pressor activity of extracts from the aortic walls of cattle have been investigated, using the extraction method described by Euler, and traces of histamine, though masked in its action on the blood pressure by the pressor substance, may cause a liberation of adrenaline in the test-animal itself.
  • L. Gunne
  • Medicine, Psychology
    Annals of the New York Academy of Sciences
  • 1962
A study of the catecholamine metabolism in rats given morphine in increasing doses for three weeks finds that these studies have been extended to include the metabolism of certain monoamines of current interest.
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Es wurden die krankhaften Zustände angeführt, bei denen Adrenalin and Sympathin in abnorm gesteigerten Mengen ins Blut and in the Herzmuskel entladen werden.


Identification of a Urine Base with Nicotine-like Action
IN a previous communication, the isolation from urine of a volatile base with nicotine-like action has been announced1. The active substance was obtained from normal fresh cow's urine by means of