The purpose of this study was to explore the professional competence for offset printing participants. Survey questionnaire methodology was used in this research. The surveyed participants in this research were the managers and supervisors of the press operators in commercial printing companies. To analyze the result of surveys, several statistical methods including frequency distribution, percentage, and T-Test were conducted. The conclusions were: 1. Thirty professional competences within four categories were identified in this study. 2. Every professional competence item has been demonstrated that the offset printing participants must have these thirty basic professional competence items.