A Structured, Dynamic Model for Animal Cell Culture: Application to Baculovirus Insect Cell Systems

@inproceedings{Sanderson1999ASD,
  title={A Structured, Dynamic Model for Animal Cell Culture: Application to Baculovirus Insect Cell Systems},
  author={C. S. Sanderson and John P. Barford and Geoff W Barton and T.K.K Wong and Steven Reid},
  year={1999}
}
Viral infection can have significant effects on the behaviour of cell cultures and the interaction of baculoviruses with insect cells is currently of particular interest. This paper examines a number of existing mathematical models for this phenomenon and describes the development of an extension to a structured model for cellular metabolism. This extension is capable of describing the effects of multiple and secondary infection, the actions of defective interfering particles and the release of… CONTINUE READING