A Structure-Based Model for Predicting Serum Albumin Binding

@inproceedings{Lexa2014ASM,
  title={A Structure-Based Model for Predicting Serum Albumin Binding},
  author={Katrina W. Lexa and Elena Dolghih and Matthew P. Jacobson},
  booktitle={PloS one},
  year={2014}
}
One of the many factors involved in determining the distribution and metabolism of a compound is the strength of its binding to human serum albumin. While experimental and QSAR approaches for determining binding to albumin exist, various factors limit their ability to provide accurate binding affinity for novel compounds. Thus, to complement the existing… CONTINUE READING