A Story of Swapped Ends

  title={A Story of Swapped Ends},
  author={J. Rowley},
  pages={1412 - 1413}
  • J. Rowley
  • Published 2013
  • Biology, Medicine
  • Science
  • Forty years ago, a chromosomal translocation was discovered to cause leukemia and revealed cancer as a genetic disease. [Also see Book Review by Nadkarni] It was dubbed the “Philadelphia chromosome,” named after the city where the abnormal chromosome was first described in 1960 (1). Peter Nowell, of the University of Pennsylvania, and David Hungerford, at the Fox Chase Cancer Center, had taken a close look at patients with chronic myeloid leukemia (CML) and found that regardless of sex, they… CONTINUE READING
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