A Stochastic Model for Microtubule Motors Describes the In Vivo Cytoplasmic Transport of Human Adenovirus

@inproceedings{Gazzola2009ASM,
  title={A Stochastic Model for Microtubule Motors Describes the In Vivo Cytoplasmic Transport of Human Adenovirus},
  author={Mattia Gazzola and Christoph J. Burckhardt and Basil Bayati and Martin Engelke and Urs F. Greber and Petros Koumoutsakos},
  booktitle={PLoS Computational Biology},
  year={2009}
}
Cytoplasmic transport of organelles, nucleic acids and proteins on microtubules is usually bidirectional with dynein and kinesin motors mediating the delivery of cargoes in the cytoplasm. Here we combine live cell microscopy, single virus tracking and trajectory segmentation to systematically identify the parameters of a stochastic computational model of… CONTINUE READING